Implementation Science Research to Improve Dental, Oral and Craniofacial Health (U01) | RFA DE 18 001

Opportunity Information: Apply for RFA DE 18 001

Implementation Science Research to Improve Dental, Oral and Craniofacial Health (U01) is a National Institutes of Health (NIH) funding opportunity that supports research focused on implementation science in dental, oral, and craniofacial health. The core goal is to speed up the real-world uptake of interventions, policies, and clinical or public health practices that already have a solid evidence base. In practical terms, the FOA is aimed at closing the common gap between what research shows works and what actually gets adopted broadly in clinics, community programs, health systems, and other care settings. Projects are expected to study strategies that improve adoption, integration, scale-up, and sustainability of proven approaches, rather than primarily developing brand-new clinical interventions.

This opportunity is offered as a cooperative agreement (U01), meaning it is not just a standard research grant where the awardee operates independently. Under a cooperative agreement, NIH typically anticipates substantial programmatic involvement during the project, such as collaboration on milestones, shared oversight, and coordination around implementation goals. The funding activity category is Health, and the listing is associated with CFDA number 93.121. The opportunity number is RFA-DE-18-001, and it was created on October 19, 2016, with an original closing date of February 21, 2017. The listed award ceiling is $500,000, indicating the maximum amount expected per award under the announcement.

The eligible applicant pool is broad and includes many types of domestic organizations and governmental entities. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; and public housing authorities or Indian housing authorities. It also includes federally recognized Native American tribal governments, as well as tribal organizations that are not federally recognized. Both nonprofit organizations (including those with 501(c)(3) status and those without 501(c)(3) status) can apply, as can for-profit organizations (other than small businesses) and small businesses. The FOA also explicitly highlights additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible federal agencies; regional organizations; and U.S. territories or possessions.

The eligibility rules around foreign participation are specific. Non-domestic (non-U.S.) entities and foreign institutions are not eligible to apply as the main applicant organization. However, non-domestic components of U.S. organizations are eligible to apply, and foreign components are allowed as defined by the NIH Grants Policy Statement. In other words, the primary awardee must be an eligible U.S.-based entity, but portions of the work may involve foreign components when justified and compliant with NIH policy.

Overall, the FOA is designed for teams that want to rigorously test and refine implementation strategies that move proven dental, oral, and craniofacial health advances into routine practice more quickly and more reliably. The emphasis is on understanding and improving the processes that drive real-world adoption, including the systems, settings, and stakeholders that affect whether evidence-based approaches are actually used at scale.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Implementation Science Research to Improve Dental, Oral and Craniofacial Health (U01)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121.
• This funding opportunity was created on 2016-10-19.
• Applicants must submit their applications by 2017-02-21. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $500,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA DE 18 001

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