Opportunity Information: Apply for RFA IP 20 003

The grant opportunity titled "Network of Modeling Centers to Improve Evidence Base for Seasonal and Pandemic Influenza Prevention and Control" (Funding Opportunity Number RFA IP 20 003) is a CDC cooperative agreement designed to strengthen the practical, decision-focused use of mathematical modeling for influenza. The central goal is to fund applied research that builds, improves, and uses models to evaluate how well different prevention and control strategies work for both routine seasonal influenza and future pandemics. The strategies of interest explicitly include vaccination and treatment, with the broader intention of helping public health leaders make faster and better-supported choices during outbreaks.

A key feature of the opportunity is the creation of a coordinated network of Influenza Modeling Centers rather than isolated, one-off modeling projects. This network approach is meant to speed up the entire modeling lifecycle: rapid model development when new questions arise, harmonization across different modeling teams so outputs are more comparable, validation to increase confidence in results, synthesis of findings across multiple models, and clear communication of results to public health stakeholders. In practice, the CDC is signaling that it values not only sophisticated models, but also processes that make multi-model evidence easier to trust and use, especially when decisions need to be made quickly under uncertainty.

The expected impact is an improved evidence base for public health action and policy development. By emphasizing rapid sharing of validated results from multiple models, the NOFO aims to reduce the delays and inconsistencies that can happen when different groups model the same problem in different ways without coordination. The intent is that converging evidence across several well-documented and validated models can provide stronger support for guidance on issues like vaccine strategy, treatment use, and other control measures during seasonal epidemics and pandemic scenarios.

Administratively, this is a discretionary funding opportunity in the health category, offered by the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC - ERA), under CFDA 93.185. The funding instrument is a cooperative agreement, which generally means the CDC anticipates substantial involvement in the funded work, such as collaboration on priorities, coordination across centers, or engagement on deliverables that support public health decision-making. The opportunity listed an award ceiling of $375,000 and anticipated making around 5 awards.

Eligibility is broad and includes many public-sector and nonprofit entities that could plausibly house modeling centers or lead multi-institution collaborations. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); and additional eligible parties as described in the full eligibility text. The NOFO was created on Aug 08, 2019, with an original application due date of Nov 15, 2019, and required electronic submission by 5:00 p.m. ET on the due date.

Taken together, the opportunity is essentially about building a durable national capability for influenza modeling that is faster, more coordinated, and more directly usable by decision-makers. Instead of rewarding modeling as an academic exercise, it prioritizes operational relevance: producing validated, comparable, and clearly communicated results that can be synthesized across multiple modeling approaches to guide influenza prevention and control policies before and during public health emergencies.

  • The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Network of Modeling Centers to Improve Evidence Base for Seasonal and Pandemic Influenza Prevention and Control" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.185.
  • This funding opportunity was created on Aug 08, 2019.
  • Applicants must submit their applications by Nov 15, 2019 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $375,000.00 in funding.
  • The number of recipients for this funding is limited to 5 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
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