Opportunity Information: Apply for RFA IP 20 003
The grant opportunity titled "Network of Modeling Centers to Improve Evidence Base for Seasonal and Pandemic Influenza Prevention and Control" (Funding Opportunity Number RFA IP 20 003) is a CDC cooperative agreement designed to strengthen the practical, decision-focused use of mathematical modeling for influenza. The central goal is to fund applied research that builds, improves, and uses models to evaluate how well different prevention and control strategies work for both routine seasonal influenza and future pandemics. The strategies of interest explicitly include vaccination and treatment, with the broader intention of helping public health leaders make faster and better-supported choices during outbreaks.
A key feature of the opportunity is the creation of a coordinated network of Influenza Modeling Centers rather than isolated, one-off modeling projects. This network approach is meant to speed up the entire modeling lifecycle: rapid model development when new questions arise, harmonization across different modeling teams so outputs are more comparable, validation to increase confidence in results, synthesis of findings across multiple models, and clear communication of results to public health stakeholders. In practice, the CDC is signaling that it values not only sophisticated models, but also processes that make multi-model evidence easier to trust and use, especially when decisions need to be made quickly under uncertainty.
The expected impact is an improved evidence base for public health action and policy development. By emphasizing rapid sharing of validated results from multiple models, the NOFO aims to reduce the delays and inconsistencies that can happen when different groups model the same problem in different ways without coordination. The intent is that converging evidence across several well-documented and validated models can provide stronger support for guidance on issues like vaccine strategy, treatment use, and other control measures during seasonal epidemics and pandemic scenarios.
Administratively, this is a discretionary funding opportunity in the health category, offered by the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC - ERA), under CFDA 93.185. The funding instrument is a cooperative agreement, which generally means the CDC anticipates substantial involvement in the funded work, such as collaboration on priorities, coordination across centers, or engagement on deliverables that support public health decision-making. The opportunity listed an award ceiling of $375,000 and anticipated making around 5 awards.
Eligibility is broad and includes many public-sector and nonprofit entities that could plausibly house modeling centers or lead multi-institution collaborations. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); and additional eligible parties as described in the full eligibility text. The NOFO was created on Aug 08, 2019, with an original application due date of Nov 15, 2019, and required electronic submission by 5:00 p.m. ET on the due date.
Taken together, the opportunity is essentially about building a durable national capability for influenza modeling that is faster, more coordinated, and more directly usable by decision-makers. Instead of rewarding modeling as an academic exercise, it prioritizes operational relevance: producing validated, comparable, and clearly communicated results that can be synthesized across multiple modeling approaches to guide influenza prevention and control policies before and during public health emergencies.Apply for RFA IP 20 003
- The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Network of Modeling Centers to Improve Evidence Base for Seasonal and Pandemic Influenza Prevention and Control" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.185.
- This funding opportunity was created on Aug 08, 2019.
- Applicants must submit their applications by Nov 15, 2019 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $375,000.00 in funding.
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs)
What is the title of this grant opportunity?
The opportunity is titled "Network of Modeling Centers to Improve Evidence Base for Seasonal and Pandemic Influenza Prevention and Control."
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is RFA IP 20 003.
Which agency is offering this funding?
This is a discretionary funding opportunity from the U.S. Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC - ERA).
What type of funding mechanism is being used?
The funding instrument is a cooperative agreement. This generally indicates substantial CDC involvement in the funded work, such as collaboration on priorities, coordination across centers, and engagement on deliverables that support public health decision-making.
What is the CFDA number for this opportunity?
The CFDA number listed for this opportunity is 93.185.
What is the central goal of the program?
The central goal is to strengthen the practical, decision-focused use of mathematical modeling for influenza by funding applied research that builds, improves, and uses models to evaluate prevention and control strategies for both routine seasonal influenza and future pandemics.
What kinds of influenza scenarios are included?
The opportunity covers both routine seasonal influenza and future pandemic influenza scenarios.
What types of strategies are explicitly of interest for evaluation?
The strategies explicitly called out include vaccination and treatment. The broader intent is to evaluate prevention and control strategies that public health leaders may need to choose among during outbreaks.
What makes this opportunity different from one-off modeling projects?
A key feature is that CDC is seeking to create a coordinated network of Influenza Modeling Centers rather than funding isolated, single projects. The network is intended to speed up and improve the overall modeling lifecycle and the usability of outputs for public health decisions.
What is meant by a "network of modeling centers" in this NOFO?
Based on the description provided, it refers to multiple modeling centers working in a coordinated way (rather than independently) so results can be developed rapidly, compared more easily, validated, synthesized across models, and communicated clearly to public health stakeholders.
Why does the NOFO emphasize coordination across centers?
The NOFO is designed to reduce delays and inconsistencies that can occur when different groups model the same problem in different ways without coordination. Coordinated work can make multi-model evidence faster to generate and easier to trust and use during time-sensitive decision-making.
What does the NOFO say about the modeling lifecycle?
The opportunity emphasizes improving the full modeling lifecycle, including rapid model development when new questions arise, harmonization across teams so outputs are more comparable, validation to increase confidence in results, synthesis of findings across multiple models, and clear communication to stakeholders.
Why is validation highlighted in the opportunity?
Validation is highlighted because it can increase confidence in model results, which is especially important when results are being used to support real-time or high-stakes public health decisions under uncertainty.
What is meant by harmonization across modeling teams?
Harmonization refers to processes that make outputs from different modeling groups more comparable. In this NOFO, harmonization is part of the broader network approach intended to support synthesis across multiple models.
What does "synthesis across multiple models" imply here?
It implies combining or comparing findings from several models to look for converging evidence. The NOFO’s intent is that shared, validated, well-documented results from multiple models can provide stronger support for public health guidance than any single model alone.
What is the intended public health impact of the program?
The intended impact is an improved evidence base for public health action and policy development, supported by rapid sharing of validated results and clearer synthesis across multiple models to guide influenza prevention and control.
How will the results be used by public health leaders?
The results are intended to help leaders make faster and better-supported choices during outbreaks, including decisions related to vaccine strategy, treatment use, and other control measures for seasonal epidemics and pandemic scenarios.
Is the NOFO focused on academic modeling or operational decision support?
The description prioritizes operational relevance over modeling as an academic exercise. It emphasizes decision-focused outputs that are validated, comparable, synthesized across models, and clearly communicated for use in public health policy and emergency response.
What is the award ceiling for this opportunity?
The listed award ceiling is $375,000.
How many awards does CDC anticipate making?
The opportunity anticipated making around 5 awards.
Who is eligible to apply?
Eligibility is broad and includes: state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories); and additional eligible parties as described in the full eligibility text.
Can institutions of higher education apply?
Yes. Public and state-controlled institutions of higher education are explicitly listed as eligible.
Are nonprofit organizations eligible?
Yes. Nonprofits with or without 501(c)(3) status are listed as eligible, with a specific note excluding institutions of higher education within those nonprofit categories.
Are tribal entities eligible?
Yes. Federally recognized Native American tribal governments and other tribal organizations are listed as eligible.
Are local government entities eligible?
Yes. State, county, and city or township governments are listed as eligible, along with special district governments and independent school districts.
Are public housing authorities eligible?
Yes. Public housing authorities/Indian housing authorities are included in the eligibility list.
When was the NOFO created?
The NOFO was created on Aug 08, 2019.
What was the original application due date?
The original application due date was Nov 15, 2019.
What time were applications due?
Electronic submission was required by 5:00 p.m. ET on the due date.
Is this opportunity specifically about influenza?
Yes. The opportunity is focused on improving the evidence base for prevention and control of seasonal and pandemic influenza through coordinated mathematical modeling.
What is the overall purpose of creating a "durable national capability" for influenza modeling?
The stated intent is to build a capability that is faster, more coordinated, and more directly usable by decision-makers, so modeling results can better support prevention and control policies before and during public health emergencies.
What role does communication play in this program?
Clear communication of results to public health stakeholders is explicitly listed as part of the network approach, alongside development, harmonization, validation, and synthesis.
What kinds of decisions could this work inform?
The opportunity notes that the evidence produced could support guidance on vaccine strategy, treatment use, and other control measures during seasonal epidemics and pandemic scenarios.
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